Zach Tyler Eisen
Lucas Nickle (voice)
Julia Roberts
Hova (voice)
Meryl Streep
Queen (voice)
Nicolas Cage
Zoc (voice)
Paul Giamatti
Stan Beals (voice)
Bruce Campbell
Fugax (voice)
Regina King
Kreela (voice)
Lily Tomlin
Mommo (voice)
Larry Miller
Fred Nickle (voice)
Cheri Oteri
Doreen Nickle (voice)
Ricardo Montalban
Head of Council (voice)
Myles Jeffrey
Steve (voice)
Creagen Dow
Mullet Boy (voice)
Frank Welker
Spindle / Frog / Caterpillar (voice)
Mark DeCarlo
Fly (voice)
Jake T. Austin
Nicky (voice)
Allison Mack
Tiffany Nickle (voice)
S. Scott Bullock
Glow Worm / Wasp Survivor (voice)
Paul Greenberg
Sleeping Ant #1 / Head Lice #1 / Head Lice #2 / Head Lice #3 / Head Lice #4 / Brett (voice)
Rob Paulsen
Beetle (voice)
Nicole Sullivan
Ant #9 (voice)
Don Frye
Soldier Ant (voice)
Larry Cedar
Ant #8 (voice)
David Kaye
Sleeping Ant #2 / Guard Ant #3 / Wrangler Ant (voice)
![Alfred Jackson]()
Alfred Jackson
Slacker Ant (voice)
![Ken Mitchroney]()
Ken Mitchroney
Ant #17 / Guard Ant #2 / Wasp #8 (voice)
Denzel Whitaker
Albert (voice)
![Casey Masamitsu]()
Casey Masamitsu
Shigeko (voice)
![Bryan Fabian]()
Bryan Fabian
Fernando (voice)
Jake Goldberg
Helmet Boy / Nob / Red Teammate #1 (voice)
![Keith Alcorn]()
Keith Alcorn
Ant #18 / Pupa / Soldier Ant #3 (voice)
John A. Davis
Ant #19 (voice)
Tom Kenny
Drone Ant / Ant #2 / Ant #6 (voice)
![Sarah Mensinga]()
Sarah Mensinga
Mother Ant (voice)
Nika Futterman
Ant #1 / Ant #7 (voice)
![Scott Holst]()
Scott Holst
Ant #3 (voice)
![Susan Silo]()
Susan Silo
Ant #4 (voice)
Paul Rugg
Ant #5 (voice)
Candi Milo
Nurse Ant #3 (voice)
![Nissa Alcorn]()
Nissa Alcorn
Billo (voice)
Pat Fraley
Ant Council #1 (voice)
Tyler James Williams
Blue Teammate #1 (voice)
![Jared Goldsmith]()
Jared Goldsmith
Blue Teammate #2 / Red Teammate #2 (voice)
Austin Majors
Blue Teammate #3 (voice)
Jaishon Fisher
Blue Teammate #4 (voice)
![Aaron Michael Drozin]()
Aaron Michael Drozin
Blue Teammate #5 (voice)
Max Burkholder
Blue Teammate #6 (voice)
![Sam Green]()
Sam Green
Red Teammate #3 (voice)
Colin Ford
Red Teammate #4 (voice)
Kendall Ryan Sanders
Red Teammate #5 (voice)
Shane Baumel
Red Teammate #6 (voice)
Neil Ross
Wasp #1 / Wasp #5 (voice)
Bob Joles
Wasp #2 (voice)
Wally Wingert
Wasp #3 (voice)
![Leon Morenzie]()
Leon Morenzie
Wasp #4 (voice)
Jonathan David Cook
Wasp #6 (voice)
Sean Donnellan
Soldier Ant #1 (voice)
Tress MacNeille
Old Council Ant (voice)
Clive Robertson
Hova's Wasp (voice)
Vernee Watson
Head Nurse (voice)
Richard Green
Wasp Leader (voice)
